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flexanalysis 4.0 software  (Bruker Corporation)


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    Structured Review

    Bruker Corporation flexanalysis 4.0 software
    Flexanalysis 4.0 Software, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/flexanalysis+4%2E0+software/flexanalysis+software/pmc10041126__pnas__2205140120__sapp-27-15-18
    Average 90 stars, based on 1 article reviews
    flexanalysis 4.0 software - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Mass Spectrometry:

    Article Title: Extracellular Vesicles Contribute to the Difference in Lipid Composition between Ovarian Follicles of Different Size Revealed by Mass Spectrometry Imaging.
    Article Snippet: To increase mass accuracy (mass error < 0.05%), internal calibration using a lock mass at m/z 760.5851 (PC34:1) for positive ion mode and m/z 885.5499 for negative ion mode was subsequently applied to all spectra, with flexAnalysis 4.0 software (Bruker) and FlexAnalysis Batch Process (Compass 2.0).

    Article Title: Fourteen-member silacycle built by cascade reactions induced by a platinum catalyst
    Article Snippet: Aiming at the synthesis of platinum complexes, a ligand containing a dimethylsilane moiety was designed by a two-step reaction, respectively Williamson ether synthesis and carbonyl-amine condensation, starting from bis(chloromethyl)dimethylsilane, 3,5-dichlorosalycylaldehyde and 2-aminophenol.. By reacting the new bis-imine with Pt(acac) 2 , an uncommon cyclic structure without metal has been obtained.. Thereby, a deep insight into the reaction mechanism and reaction conditions was required, the 2D NMR and MALDI-MS studies revealing the rearrangement processes and cascade reactions that occur in three main steps, respectively imine cleavage, aldol condensation, and a new imine bond formation.

    Article Title: LPS-induced lipid alterations in microglia revealed by MALDI mass spectrometry-based cell fingerprinting in neuroinflammation studies
    Article Snippet: Processing of MALDI-TOF MS mass spectra and data analysis in negative ion mode To verify differences in vehicle (VEH)-treated versus lipopolysaccharide (LPS)-stimulated microglia cells, the workflow for MALDI-TOF MS data processing and analysis consisted of an initial manual recalibration of mass spectra in flexAnalysis 4.0 software (Bruker Daltonics).

    Article Title: Tracking the disulfide rearrangement of heated lactoglobulin by matrix-assisted laser desorption/ionization-in-source decay top-down analysis.
    Article Snippet: Funding information Shenzhen Bay Laboratory, Grant/Award Number: SZBL2020090501001; Guangxi University, Grant/Award Number: A3040051029 Abstract Disulfide bond rearrangement is a common occurrence during protein analysis or treatment.. A convenient and rapid method has been developed to investigate heat-induced disulfide rearrangement of lactoglobulin using matrix-assisted laser desorption/ionization-in-source decay (MALDI-ISD) technology.. By analyzing heated lactoglobulin in reflectron and linear mode, we demonstrated that cysteines C66 and C160 exist as free residues other than linked ones in some protein isomers.

    Article Title: MALDI-TOF mass spectrometry for direct KPC detection among Enterobacterales.
    Article Snippet: Analyses were performed using a Microflex LT mass spectrometer (Bruker Daltonics) and flexAnalysis 4.0 software (Bruker Daltonics).

    Article Title: Generation of CRISPR/Cas9-mediated null mutants The BaraA (CG18279) and CG18278 null mutants were generated using CRISPR/Cas9 technology based on the expression of gRNA transgenes that were then crossed to a transgenic line expressing a pnos-Cas9 transgene. The 20bp-long gRNAs for the target genes were devised using web-based CRISPR Optimal Target Finder (http://targetfinder.flycrispr.neuro.brown.edu/). The plasmids carrying DNA sequences for the production of single strand gRNAs
    Article Snippet: All of the recorded spectra were processed with a baseline subtraction and spectral smoothing using FlexAnalysis 4.0 software (Bruker Daltonics Inc.).

    Article Title: LPS-induced lipid alterations in microglia revealed by MALDI mass spectrometry-based cell fingerprinting in neuroinflammation studies
    Article Snippet: Initial manual recalibration of mass spectra was done in flexAnalysis 4.0 software (Bruker Daltonics, Bremen, Germany).

    Article Title: Preferred β-lactone synthesis can explain high rate of false-negative results in the detection of OXA-48-like carbapenemases
    Article Snippet: Spectra were measured within the m/z range 300–500 using a microflex LT and rapifleX mass spectrometers (Bruker Daltonics, Bremen, Germany) and analyzed by the flexAnalysis 4.0 software.

    Software:

    Article Title: Extracellular Vesicles Contribute to the Difference in Lipid Composition between Ovarian Follicles of Different Size Revealed by Mass Spectrometry Imaging.
    Article Snippet: To increase mass accuracy (mass error < 0.05%), internal calibration using a lock mass at m/z 760.5851 (PC34:1) for positive ion mode and m/z 885.5499 for negative ion mode was subsequently applied to all spectra, with flexAnalysis 4.0 software (Bruker) and FlexAnalysis Batch Process (Compass 2.0).

    Article Title: Fourteen-member silacycle built by cascade reactions induced by a platinum catalyst
    Article Snippet: Aiming at the synthesis of platinum complexes, a ligand containing a dimethylsilane moiety was designed by a two-step reaction, respectively Williamson ether synthesis and carbonyl-amine condensation, starting from bis(chloromethyl)dimethylsilane, 3,5-dichlorosalycylaldehyde and 2-aminophenol.. By reacting the new bis-imine with Pt(acac) 2 , an uncommon cyclic structure without metal has been obtained.. Thereby, a deep insight into the reaction mechanism and reaction conditions was required, the 2D NMR and MALDI-MS studies revealing the rearrangement processes and cascade reactions that occur in three main steps, respectively imine cleavage, aldol condensation, and a new imine bond formation.

    Article Title: LPS-induced lipid alterations in microglia revealed by MALDI mass spectrometry-based cell fingerprinting in neuroinflammation studies
    Article Snippet: Processing of MALDI-TOF MS mass spectra and data analysis in negative ion mode To verify differences in vehicle (VEH)-treated versus lipopolysaccharide (LPS)-stimulated microglia cells, the workflow for MALDI-TOF MS data processing and analysis consisted of an initial manual recalibration of mass spectra in flexAnalysis 4.0 software (Bruker Daltonics).

    Article Title: Tracking the disulfide rearrangement of heated lactoglobulin by matrix-assisted laser desorption/ionization-in-source decay top-down analysis.
    Article Snippet: Funding information Shenzhen Bay Laboratory, Grant/Award Number: SZBL2020090501001; Guangxi University, Grant/Award Number: A3040051029 Abstract Disulfide bond rearrangement is a common occurrence during protein analysis or treatment.. A convenient and rapid method has been developed to investigate heat-induced disulfide rearrangement of lactoglobulin using matrix-assisted laser desorption/ionization-in-source decay (MALDI-ISD) technology.. By analyzing heated lactoglobulin in reflectron and linear mode, we demonstrated that cysteines C66 and C160 exist as free residues other than linked ones in some protein isomers.

    Article Title: MALDI-TOF mass spectrometry for direct KPC detection among Enterobacterales.
    Article Snippet: Analyses were performed using a Microflex LT mass spectrometer (Bruker Daltonics) and flexAnalysis 4.0 software (Bruker Daltonics).

    Article Title: Generation of CRISPR/Cas9-mediated null mutants The BaraA (CG18279) and CG18278 null mutants were generated using CRISPR/Cas9 technology based on the expression of gRNA transgenes that were then crossed to a transgenic line expressing a pnos-Cas9 transgene. The 20bp-long gRNAs for the target genes were devised using web-based CRISPR Optimal Target Finder (http://targetfinder.flycrispr.neuro.brown.edu/). The plasmids carrying DNA sequences for the production of single strand gRNAs
    Article Snippet: All of the recorded spectra were processed with a baseline subtraction and spectral smoothing using FlexAnalysis 4.0 software (Bruker Daltonics Inc.).

    Article Title: LPS-induced lipid alterations in microglia revealed by MALDI mass spectrometry-based cell fingerprinting in neuroinflammation studies
    Article Snippet: Initial manual recalibration of mass spectra was done in flexAnalysis 4.0 software (Bruker Daltonics, Bremen, Germany).

    Article Title: Preferred β-lactone synthesis can explain high rate of false-negative results in the detection of OXA-48-like carbapenemases
    Article Snippet: Spectra were measured within the m/z range 300–500 using a microflex LT and rapifleX mass spectrometers (Bruker Daltonics, Bremen, Germany) and analyzed by the flexAnalysis 4.0 software.



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